Postdoctoral research
Marmont LS, Orta AK, Baileeves BWA, Sychantha D, Fernández-Galliano A, Li YE, Greene NG, Corey RA, Stansfeld PJ, Clemons WM Jr, and Bernhardt TG. (2024) Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa. Nature Microbiology. doi: 10.1038/s41564-024-01603-2.
Marmont LS and Bernhardt TG. (2020). A conserved subcomplex within the bacterial cytokinetic ring activates cell wall synthesis by the FtsW-FtsI synthase. Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.2004598117.
Taguchi A, Welsh MA, Marmont LS, Lee W, Sjodt M, Kruse AC, Kahne D, Bernhardt TG, Walker S. (2019) FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein. Nature Microbiology. doi: 10.1038/s41564-018-0345-x.
Graduate school research
Marmont LS*, Whitfield GB*, Pfoh R, Williams RJ, Randall T, Ostaszewski A, Razvi E, Robinson H, Nitz M, Parsek MR, Lewis I, Whitney JC, Harrison JJ, Howell PL. (2020) PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation. Journal of Biological Chemistry. doi: 10.1074/jbc.RA120.014555. *authors contributed equally to this work. Selected as one of Editors Picks, and image also selected for the cover. Our article is featured in a special virtual issue of JBC highlighting women in biological chemistry (https://www.jbc.org/women-in-bc) with our figure adapted for the cover art.
Bundalovic-Torma C, Whitfield GB, Marmont LS, Howell PL, and Parkinson J. (2020) A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries. PLoS Computational Biology. doi: 10.1371/journal.pcbi.1007721.
Whitfield GB, Marmont LS, Bundalovic-Torma C, Razvi E, Roach EJ, Khursigara CM, Parkinson J, and Howell PL. (2020) Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster. PLoS Pathogens. doi: 10.1371/journal.ppat.1008281.
Whitfield GB, Marmont LS, Ostaszewski A, Rich JD, Whitney JC, Parsek MR, Harrison JJ, Howell PL. (2020) Pel polysaccharide biosynthesis requires an inner membrane complex comprised of PelD, PelE, PelF and PelG. Journal of Bacteriology. doi: 10.1128/JB.00684-19.
Marmont LS, Whitfield GB, Rich JD, Yip P, Giesbrecht LB, Stremick CA, Whitney JC, Parsek MR, Harrison JJ, Howell PL. (2017) PelA and PelB form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa. The Journal of Biological Chemistry. doi: 10.1074/jbc.M117.812842.
Marmont LS, Rich JD, Whitney JC, Whitfield GB, Almblad H, Robinson H, Parsek MR, Harrison JJ, Howell PL. (2017) Oligomeric lipoprotein PelC guides Pel polysaccharide export across the outer membrane of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1613606114.
Jennings LK, Storek KM, Ledvina HE, Coulon, C, Marmont LS, Sadovskaya I, Secor PR, Tseng BS, Scian M, Filloux A, Wozniak DJ, Howell PL, Parsek MR. (2015) Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix. Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1503058112.
Whitfield GB*, Marmont LS*, Howell PL. (2015) Enzymatic modifications of exopolysaccharides enhance bacterial persistence. Frontiers in Microbiology. doi: 10.3389/fmicb.2015.00471. *authors contributed equally to this work.
Whitney JC, Whitfield GB, Marmont LS, Yip P, Neculai AM, Lobsanov YD, Robinson H, Ohman DE, Howell PL. (2015) Dimeric c-di-GMP is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa. The Journal of Biological Chemistry. doi: 10.1074/jbc.M115.645051.
Undergraduate research
Whitney JC, Colvin KM, Marmont LS, Robinson H, Parsek, MR, Howell PL. (2012) Structure of the cytoplasmic region of PelD, a degenerate diguanylate cyclase receptor that regulates exopolysaccharide production in Pseudomonas aeruginosa. The Journal of Biological Chemistry. doi: 10.1074/jbc.M112.375378.
Marmont LS, Whitney JC, Robinson H, Colvin KM, Parsek MR, Howell PL. (2012) Expression, purification, crystallization, and preliminary X-ray analysis of Pseudomonas aeruginosa PelD. Acta Crystallographica Section F. doi: 10.1107/S1744309111052109.